Microgranular acute promyelocytic leukemia with concurrent FLT3-TKD mutation and MYC amplification: expanding the genomic spectrum and guiding personalized therapy

Abstract Background Acute promyelocytic leukemia (APL) is highly curable with targeted therapy combining all-trans retinoic acid (ATRA) and arsenic trioxide, yet the microgranular variant (M3v) frequently mimics monocytic leukemia and may delay diagnosis. Although FLT3 internal tandem duplications a...

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Detaylı Bibliyografya

Yazar:	Yousef VatanParast
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Springer 2026-07-01
Seri Bilgileri:	Journal of Rare Diseases
Konular:	Acute promyelocytic leukemia Microgranular variant FLT3-TKD mutation MYC amplification PML:RARA Gemtuzumab ozogamicin
Online Erişim:	https://doi.org/10.1007/s44162-026-00217-y
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