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Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients

Circularized transcript isoforms due to back-splicing are increasingly being reported in different tissues types and pathological states including cancer. Since these circular RNAs (circRNAs) are more stable than linear messenger RNA their identification and profiling in tumor tissue could aid in st...

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Hlavní autoři: Anshita Goel, Douglas G. Ward, Naheema S. Gordon, Ben Abbotts, Maurice P. Zeegers, K. K. Cheng, Nicholas D. James, Richard T. Bryan, Roland Arnold
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020-05-01
Edice:Frontiers in Oncology
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On-line přístup:https://www.frontiersin.org/article/10.3389/fonc.2020.00812/full
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