Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients

Circularized transcript isoforms due to back-splicing are increasingly being reported in different tissues types and pathological states including cancer. Since these circular RNAs (circRNAs) are more stable than linear messenger RNA their identification and profiling in tumor tissue could aid in st...

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Autori principali:	Anshita Goel, Douglas G. Ward, Naheema S. Gordon, Ben Abbotts, Maurice P. Zeegers, K. K. Cheng, Nicholas D. James, Richard T. Bryan, Roland Arnold
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2020-05-01
Serie:	Frontiers in Oncology
Soggetti:	circular RNA back-splicing bladder cancer tumor grade NMIBC biomarkers
Accesso online:	https://www.frontiersin.org/article/10.3389/fonc.2020.00812/full
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