QR Code

Apremilast improves cardiomyocyte cohesion and arrhythmia in different models for arrhythmogenic cardiomyopathy

Abstract Background Arrhythmogenic cardiomyopathy (ACM) is a genetically inherited desmosome heart disease leading to life-threatening arrhythmias and sudden cardiac death. Currently, ACM treatment paradigms are merely symptom targeting. Recently, apremilast was shown to stabilize keratinocyte adhes...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Konstanze Stangner, Orsela Dervishi, Janina Kuhnert, Carl Wendt, Soumyata Pathak, Maria Shoykhet, Silvana Olivares-Florez, Sina Moztarzadeh, Jens Opsteen, Ni Luh Cathrin Suniasih Wohlfarth, Ruth Biller, Elisabeth Graf, Dominik S. Westphal, Tatjana Williams, Brenda Gerull, Tomo Šarić, Sunil Yeruva, Jens Waschke
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-11-01
Rangatū:Stem Cell Research & Therapy
Ngā marau:
Apremilast
Arrhythmogenic cardiomyopathy
Arrhythmia
Desmoplakin and desmoglein 2
Urunga tuihono:https://doi.org/10.1186/s13287-025-04755-y
Ngā Tūtohu: Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!

Ngā tūemi rite