Novel Thiazole-Fused [4,5-<i>g</i>] or [5,4-<i>g</i>]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation

<b>Background/Objectives:</b> In connection with previous work on V-shaped polycyclic thiazolo[5,4-<i>f</i>]quinazolin-9-one and [5,4-<i>f</i>]quinazoline derivatives that can modulate the activity of various kinases, the synthesis of straight thiazole-fused [4,5-<i>g</i>] or [5,4-<i>g</i>]quinazoli...

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Auteurs principaux:	Nathan Broudic, Alexandra Pacheco-Benichou, Cécile Corbière, Blandine Baratte, Thomas Robert, Stéphane Bach, Hélène Solhi, Rémy Le Guével, Corinne Fruit, Thierry Besson
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2024-10-01
Collection:	Pharmaceuticals
Sujets:	thiazoloquinazolinones thiazoloquinazolines 4,5-dichloro-1,2,3-dithiazolium chloride microwave-assisted chemistry cytotoxicity kinase inhibition
Accès en ligne:	https://www.mdpi.com/1424-8247/17/11/1452
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