Novel Thiazole-Fused [4,5-<i>g</i>] or [5,4-<i>g</i>]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation

<b>Background/Objectives:</b> In connection with previous work on V-shaped polycyclic thiazolo[5,4-<i>f</i>]quinazolin-9-one and [5,4-<i>f</i>]quinazoline derivatives that can modulate the activity of various kinases, the synthesis of straight thiazole-fused [4,5-<i>g</i>] or [5,4-<i>g</i>]quinazoli...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Nathan Broudic, Alexandra Pacheco-Benichou, Cécile Corbière, Blandine Baratte, Thomas Robert, Stéphane Bach, Hélène Solhi, Rémy Le Guével, Corinne Fruit, Thierry Besson
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2024-10-01
Cyfres:	Pharmaceuticals
Pynciau:	thiazoloquinazolinones thiazoloquinazolines 4,5-dichloro-1,2,3-dithiazolium chloride microwave-assisted chemistry cytotoxicity kinase inhibition
Mynediad Ar-lein:	https://www.mdpi.com/1424-8247/17/11/1452
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!