Identification of Novel Inhibitors of <i>Escherichia coli</i> DNA Ligase (LigA)
Present in all organisms, DNA ligases catalyse the formation of a phosphodiester bond between a 3′ hydroxyl and a 5′ phosphate, a reaction that is essential for maintaining genome integrity during replication and repair. Eubacterial DNA ligases use NAD<sup>+</sup> as a cofactor and possess low seque...
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| Hoofdauteurs: | , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
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MDPI AG
2021-04-01
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| Reeks: | Molecules |
| Onderwerpen: | |
| Online toegang: | https://www.mdpi.com/1420-3049/26/9/2508 |
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