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Conservation of Glutathione Transferase mRNA and Protein Sequences Similar to Human and Horse Alpha Class GST A3-3 across Dog, Goat, and Opossum Species

The glutathione transferase A3-3 (GST A3-3) homodimeric enzyme is the most efficient enzyme that catalyzes isomerization of the precursors of testosterone, estradiol, and progesterone in the gonads of humans and horses. However, the presence of GST A3-3 orthologs with equally high ketosteroid isomer...

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Principais autores: Shawna M. Hubert, Paul B. Samollow, Helena Lindström, Bengt Mannervik, Nancy H. Ing
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-09-01
Serier:Biomolecules
Fag:
estrogen
glutathione transferase A3-3 (GST A3-3)
steroidogenesis
testes
testosterone
progesterone
Online adgang:https://www.mdpi.com/2218-273X/13/9/1420
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