Marmoset glutathione transferases with ketosteroid isomerase activity

The common marmoset Callithrix jacchus encodes two glutathione transferase (GST) enzymes with ketosteroid double-bond isomerase activity. The most active enzyme is CjaGST A3-3 showing a specific activity with 5-androsten-3,17-dione (Δ5-AD) of 62.1 ± 1.8 μmol min-1 mg-1, and a kcat value of 261 ± 49...

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Prif Awduron:	Aram Ismail, Julia Sawmi, Bengt Mannervik
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2021-09-01
Cyfres:	Biochemistry and Biophysics Reports
Pynciau:	5-Androsten-3,17-dione 5-Pregnen-3,20-dione CjaGST A3-3 CjaGST A1-1 Alpha glutathione transferase Steroid hormone synthesis
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2405580821001722
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