Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages

Macrophage-derived lipases are associated with atherosclerosis in human and animal studies. Despite numerous non-lipid-lowering effects of statins, their effect on macrophage LPL and endothelial lipase (EL) expression has not been investigated. In the present study, atorvastatin and simvastatin dose...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Guosong Qiu, John S. Hill
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2007-10-01
coleção:	Journal of Lipid Research
Assuntos:	3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor simvastatin Rho protein liver X receptor nuclear factor κB
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520424563
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!