Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages

Macrophage-derived lipases are associated with atherosclerosis in human and animal studies. Despite numerous non-lipid-lowering effects of statins, their effect on macrophage LPL and endothelial lipase (EL) expression has not been investigated. In the present study, atorvastatin and simvastatin dose...

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Detalles Bibliográficos

Principais autores:	Guosong Qiu, John S. Hill
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2007-10-01
Series:	Journal of Lipid Research
Assuntos:	3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor simvastatin Rho protein liver X receptor nuclear factor κB
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0022227520424563
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