Single-cell genomic analysis of cancer cells from one treatment-naïve patient with metastatic prostate cancer

Abstract Background Prostate cancer is among the most prevalent malignancies in men and a leading cause of cancer mortality worldwide. While localized prostate cancer is often curable, progression to metastatic and castration-resistant disease either in lymph nodes or bone/bone marrow remains the ma...

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Autores principales:	Juan Jovel, Bernhard Polzer, Jordan Patterson, Hou Yong, Catalina Vasquez, Sandra O’keefe, Desmond Pink, Guibo Li, Adrian Fairey, Benjamin Adam, Jeremy Teitelbaum, Amir Salimi, Stefan Kirsh, Barbara Alberter, Lori Lowes, Eric Carpenter, Michael Kolinsky, Zhongyi Zhu, Qing Zhou, Peter Venner, Christopher Venner, David Williams, Alison Allan, Paul C. Boutros, Christoph A. Klein, Gane Wong, John D. Lewis
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2026-05-01
Colección:	BMC Genomic Data
Materias:	Single-cell genomics Prostate cancer Metastasis Circulating tumor cells Disseminated tumor cells Copy number aberrations
Acceso en línea:	https://doi.org/10.1186/s12863-026-01435-5
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