Tertiary lymphoid structures gene signature predicts response to immunotherapy plus chemotherapy in advanced non-small cell lung cancer

Abstract Background Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, with chemoimmunotherapy (CIT) as the first-line standard for advanced NSCLC without driver mutations. However, predictive biomarkers for CIT response are limited. Tertiary lymphoid structures...

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Κύριοι συγγραφείς:	Wei Du, Bijing Xiao, Xuan Yang, Jianhua Zhan, Haishuang Sun, Yunpeng Yang, Wenfeng Fang, Yan Huang, Dongchen Sun, Shaodong Hong, Li Zhang
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Springer 2025-09-01
Σειρά:	Cancer Immunology, Immunotherapy
Θέματα:	Non-small cell lung cancer Platinum-based chemotherapy combined with immunotherapy First-line Tertiary lymphoid structures
Διαθέσιμο Online:	https://doi.org/10.1007/s00262-025-04165-2
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