IL-21 receptor signaling is essential for control of hepatocellular carcinoma growth and immunological memory for tumor challenge

Hepatocellular carcinoma (HCC) is a typical inflammation-associated cancer. IL-21 regulates both innate and adaptive immune responses and has key roles in antitumor and antiviral responses. However, the role of IL-21 in HCC development is poorly defined. In the current study, we explored the role of...

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Autori principali:	Xinchun Zheng, Yang Zhou, Xuan Yi, Chengcong Chen, Chunhua Wen, Guofu Ye, Xiaoyi Li, Libo Tang, Xiaoyong Zhang, Fuqiang Yang, Guangze Liu, Yongyin Li, Jinlin Hou
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2018-12-01
Serie:	OncoImmunology
Soggetti:	il-21 receptor hcc immune memory response mouse hcc model tumor-specific immune response
Accesso online:	http://dx.doi.org/10.1080/2162402X.2018.1500673
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