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PTPN1 is a prognostic biomarker related to cancer immunity and drug sensitivity: from pan-cancer analysis to validation in breast cancer

BackgroundProtein tyrosine phosphatase non-receptor type 1 (PTPN1), a member of the protein tyrosine phosphatase superfamily, has been identified as an oncogene and therapeutic target in various cancers. However, its precise role in determining the prognosis of human cancer and immunological respons...

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Main Authors: Ruijun Zhao, Shuanglong Chen, Weiheng Cui, Chaoyu Xie, Aiping Zhang, Li Yang, Hongmei Dong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
pan-cancer
PTPN1
prognosis
tumor microenvironment
immunotherapy
drug sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1232047/full
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