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Preparation of <i>trans</i>-Crocetin with High Solubility, Stability, and Oral Bioavailability by Incorporation into Three Types of Cyclodextrins

Crocetin (CRT), an active compound isolated from saffron, exhibits several pharmacological activities, including anti-tumor and immune-regulatory activities, and is effective against myocardial ischemia and coronary heart disease; however, its low stability and solubility limit its clinical applicat...

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Principais autores: Nan Liu, Jie Xiao, Ling-He Zang, Peng Quan, Dong-Chun Liu
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2023-12-01
סדרה:Pharmaceutics
נושאים:
crocetin
inclusion complex
solubility
dissolution
stability
oral bioavailability
גישה מקוונת:https://www.mdpi.com/1999-4923/15/12/2790
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