Preparation of <i>trans</i>-Crocetin with High Solubility, Stability, and Oral Bioavailability by Incorporation into Three Types of Cyclodextrins

Crocetin (CRT), an active compound isolated from saffron, exhibits several pharmacological activities, including anti-tumor and immune-regulatory activities, and is effective against myocardial ischemia and coronary heart disease; however, its low stability and solubility limit its clinical applicat...

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Detalhes bibliográficos

Principais autores:	Nan Liu, Jie Xiao, Ling-He Zang, Peng Quan, Dong-Chun Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-12-01
coleção:	Pharmaceutics
Assuntos:	crocetin inclusion complex solubility dissolution stability oral bioavailability
Acesso em linha:	https://www.mdpi.com/1999-4923/15/12/2790
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