FGF/FGFR1,2 targeting can attenuate lung parenchymal and vascular remodeling: an opportunity for drug repurposing against chronic lung disease and post COVID‐19 sequelae
Abstract Purpose The fibroblast growth factor and its receptors (FGF/FGFR-1,2) are expressed in lung mesenchyme and vasculature in chronic lung diseases (DPLD). They form complexes with ECM, vessels and fine-tune epithelial/endothelial cell proliferation and regeneration. Therefore they may prove to...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2025-09-01
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| Col·lecció: | Surgical and Experimental Pathology |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s42047-025-00202-7 |
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