Activity of STAMP inhibitors in ABL2 rearranged acute lymphoblastic leukemia is dependent on the Abl2 SH3 domain

Abstract: ABL2 rearranged (ABL2r) acute lymphoblastic leukemia (ALL) is a subtype of high-risk Philadelphia chromosome–like ALL. Patients with ABL2r ALL are treated with high-dose multiagent chemotherapy, and the addition of tyrosine kinase inhibitors to their treatment regimen is currently being ex...

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Detalhes bibliográficos

Principais autores:	Elias Lagonik, Elyse C. Page, John B. Bruning, Laura N. Eadie, Susan L. Heatley, Matthew Greenwood, Chun Y. Fong, Andrew S. Moore, David T. Yeung, Timothy P. Hughes, Deborah L. White
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-08-01
Colecção:	Blood Neoplasia
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2950328025000445
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