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Activity of STAMP inhibitors in ABL2 rearranged acute lymphoblastic leukemia is dependent on the Abl2 SH3 domain

Abstract: ABL2 rearranged (ABL2r) acute lymphoblastic leukemia (ALL) is a subtype of high-risk Philadelphia chromosome–like ALL. Patients with ABL2r ALL are treated with high-dose multiagent chemotherapy, and the addition of tyrosine kinase inhibitors to their treatment regimen is currently being ex...

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Autors principals: Elias Lagonik, Elyse C. Page, John B. Bruning, Laura N. Eadie, Susan L. Heatley, Matthew Greenwood, Chun Y. Fong, Andrew S. Moore, David T. Yeung, Timothy P. Hughes, Deborah L. White
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2025-08-01
Col·lecció:Blood Neoplasia
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2950328025000445
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