Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage.

The Rgcs1 quantitative trait locus, on mouse chromosome 5, influences susceptibility of retinal ganglion cells to acute damage of the optic nerve. Normally resistant mice (DBA/2J) congenic for the susceptible allele from BALB/cByJ mice exhibit susceptibility to ganglion cells, not only in acute opti...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Joel A Dietz, Margaret E Maes, Shuang Huang, Brian S Yandell, Cassandra L Schlamp, Angela D Montgomery, R Rand Allingham, Michael A Hauser, Robert W Nickells
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2014-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093564&type=printable
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