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Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric

<p>Abstract</p> <p>Background</p> <p>Glaucoma is a chronic neurodegenerative disease of the retina, characterized by the degeneration of axons in the optic nerve and retinal ganglion cell apoptosis. DBA/2J inbred mice develop chronic hereditary glaucoma and are an important model system to study the...

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Bibliografiske detaljer
Principais autores: Janssen Katherine T, Dietz Joel A, Li Yan, Schlamp Cassandra L, Nickells Robert W
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2006-10-01
Serier:BMC Neuroscience
Online adgang:http://www.biomedcentral.com/1471-2202/7/66
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