MSC-derived microvesicles inhibit the progression of arthritis in a murine model of preclinical rheumatoid arthritis

ObjectivePreclinical rheumatoid arthritis (Pre-RA) represents a critical stage before the clinical manifestation of RA, characterized by autoimmune dysregulation. Early intervention in this stage can prevent the progression to full-blown RA. This study aimed to develop a robust murine model of Pre-R...

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Detalhes bibliográficos

Principais autores:	Wei Shixiong, Ruijuan Cheng, Chengyang Lu, Qiuping Zhang, Su Jia Li, Zhi-Hui Liu, QiuHong Wu, Shu-Yue Pan, Qiubai Li, Xiao-Feng Zeng, Yi Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-02-01
coleção:	Frontiers in Immunology
Assuntos:	preclinical rheumatoid arthritis immunomodulation inflammation mesenchymal stem cells microvesicles preclinical CIA model
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1723572/full
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