Microvesicle-camouflaged biomimetic nanoparticles encapsulating a metal-organic framework for targeted rheumatoid arthritis therapy

Abstract Background Methotrexate (MTX) has been highlighted for Rheumatoid arthritis (RA) treatment, however, MTX does not accumulate well at inflamed sites, and long-term administration in high doses leads to severe side effects. In this study, a novel anti-RA nanoparticle complex was designed and...

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Principais autores:	Yao Wang, Ming Jia, Xiu Zheng, Chenglong Wang, Yun Zhou, Hong Pan, Yan Liu, Ji Lu, Zhiqiang Mei, Chunhong Li
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2022-06-01
Serija:	Journal of Nanobiotechnology
Teme:	Rheumatoid arthritis Metal–organic framework Microvesicles Folate receptor
Online dostop:	https://doi.org/10.1186/s12951-022-01447-0
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