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Folate receptor-targeted mixed polysialic acid micelles for combating rheumatoid arthritis: in vitro and in vivo evaluation

Objective: Rheumatoid arthritis (RA) is associated with chronic inflammation. The suppression of inflammation is key to the treatment of RA. Glucocorticoids (GCs) are classical anti-inflammatory drugs with several disadvantages such as poor water solubility and low specificity in the body. These dis...

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Principais autores: Nan Zhang, Chunyu Xu, Na Li, Shasha Zhang, Lingling Fu, Xiao Chu, Haiying Hua, Xianghui Zeng, Yongxing Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2018-01-01
Serier:Drug Delivery
Fag:
polysialic acid
micelles
rheumatoid arthritis
dexamethasone
folic acid
Online adgang:http://dx.doi.org/10.1080/10717544.2018.1472677
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