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Antifungal activity of 6-substituted amiloride and hexamethylene amiloride (HMA) analogs

Fungal infections have become an increasing threat as a result of growing numbers of susceptible hosts and diminishing effectiveness of antifungal drugs due to multi-drug resistance. This reality underscores the need to develop novel drugs with unique mechanisms of action. We recently identified 5-(...

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Hlavní autoři: Kiem Vu, Benjamin J. Buckley, Richard S. Bujaroski, Eduardo Blumwald, Michael J. Kelso, Angie Gelli
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2023-02-01
Edice:Frontiers in Cellular and Infection Microbiology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1101568/full
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