Fluorescence properties of the Na+/H+exchanger inhibitor HMA (5-(N,N-hexamethylene)amiloride) are modulated by intracellular pH

HMA (5-(N,N-hexamethylene)amiloride), which belongs to a family of novel amiloride derivatives, is one of the most effective inhibitors of Na+/H+ exchangers, while uneffective against Na+ channels and Na+/Ca2+ exchangers. In this study, we provided evidence that HMA can act as a fluorescent probe. I...

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Prif Awduron:	V. Giansanti, G. Santamaria, A. Torriglia, F. Aredia, A.I. Scovassi, G. Bottiroli, A.C. Croce
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	PAGEPress Publications 2012-01-01
Cyfres:	European Journal of Histochemistry
Pynciau:	ARPE19-cells, autofluorescence, HMA, intracellular pH, fluorochrome, spectroscopy, imaging
Mynediad Ar-lein:	http://www.ejh.it/index.php/ejh/article/view/1935
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!