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Safety threshold of intravitreal clonidine in rabbit’s eyes

AIM: To determine the safe dose of intravitreal clonidine (IVC), a potential drug for neuroprotection and angiogenesis inhibition in rabbits. METHODS: A total of 28 rabbits were divided into four groups. Three groups received IVC with concentrations of 15 (Group A), 25 (Group B), and 50 (Group C) µ...

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Principais autores: Homayoun Nikkhah, Kiumars Heidari Garfami, Mozhgan Rezaei Kanavi, Ebrahim Mohammad Nashtaei, Saeed Karimi, Masoud Soheilian
Format: Artigo
Sprog:Inglês
Udgivet: Press of International Journal of Ophthalmology (IJO PRESS) 2018-01-01
Serier:International Journal of Ophthalmology
Fag:
30
clonidine
intravitreal injection
electroretinography
glial fibrillary acidic protein
TUNEL assay
Online adgang:http://www.ijo.cn/en_publish/2018/1/20180105.pdf
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