Identification of Transcriptomic Differences in Induced Pluripotent Stem Cells and Neural Progenitors from Amyotrophic Lateral Sclerosis Patients Carrying Different Mutations: A Pilot Study

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting motor neurons with a phenotypic and genetic heterogeneity and elusive molecular mechanisms. With the present pilot study, we investigated different genetic mutations (<i>C9orf72</i>, <i>TARDBP</i>, and <i>KIF5A<...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Chiara Sgromo, Martina Tosi, Cristina Olgasi, Fabiola De Marchi, Francesco Favero, Giorgia Venturin, Beatrice Piola, Alessia Cucci, Lucia Corrado, Letizia Mazzini, Sandra D’Alfonso, Antonia Follenzi
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2025-06-01
Rangatū:	Cells
Ngā marau:	Amyotrophic lateral sclerosis induced pluripotent stem cells transcriptomic analysis RNA-seq neural progenitor cells
Urunga tuihono:	https://www.mdpi.com/2073-4409/14/13/958
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!