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The antibody genetics of multiple sclerosis: comparing next-generation sequencing to Sanger sequencing

We previously identified a distinct mutation pattern in the antibody genes of B cells isolated from cerebrospinal fluid (CSF) that can identify patients who have relapsing-remitting multiple sclerosis (RRMS) and patients with clinically isolated syndromes (CIS) that will convert to RRMS. This antibo...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: William eRounds, Ann eLigocki, Mikhail eLevin, Benjamin eGreenberg, Doug eBigwood, Eric eEastman, Lindsay eCowell, Nancy eMonson
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2014-09-01
Seri Bilgileri:Frontiers in Neurology
Konular:
Multiple Sclerosis
B cell
Next-generation sequencing
antibody
Roche 454
Online Erişim:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00166/full
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