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Localising loci underlying complex trait variation using Regional Genomic Relationship Mapping.

The limited proportion of complex trait variance identified in genome-wide association studies may reflect the limited power of single SNP analyses to detect either rare causative alleles or those of small effect. Motivated by studies that demonstrate that loci contributing to trait variation may co...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Yoshitaka Nagamine, Ricardo Pong-Wong, Pau Navarro, Veronique Vitart, Caroline Hayward, Igor Rudan, Harry Campbell, James Wilson, Sarah Wild, Andrew A Hicks, Peter P Pramstaller, Nicholas Hastie, Alan F Wright, Chris S Haley
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0046501&type=printable
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