Identification of Enolase as the Target of 2-Aminothiazoles in Mycobacterium tuberculosis

Tuberculosis is a massive global burden and Mycobacterium tuberculosis is increasingly resistant to first- and second-line drugs. There is an acute need for new anti-mycobacterial drugs with novel targets. We previously evaluated a series of 2-aminothiazoles with activity against Mycobacterium tuber...

Description complète

Détails bibliographiques

Auteurs principaux:	Heather H. Wescott, Edison S. Zuniga, Anumita Bajpai, Carolina Trujillo, Sabine Ehrt, Dirk Schnappinger, David M. Roberts, Tanya Parish
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2018-10-01
Collection:	Frontiers in Microbiology
Sujets:	anti-bacterial activity glycolysis drug target tuberculosis drug target discovery anti-tubercular
Accès en ligne:	https://www.frontiersin.org/article/10.3389/fmicb.2018.02542/full
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!