Muribaculum intestinale alleviates depressive-like behaviors by inhibiting Th17 cell differentiation and M1 microglia polarization

Abstract Background Gut microbiota dysbiosis has been implicated in the pathogenesis of depression. Our previous studies identified loganin as a potential antidepressant agent; however, its oral bioavailability is low. Whether loganin alleviates depression via modulation of the gut microbiota remain...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Jun He, Man-Ni Wang, Hong-Jin Chen, Guo-Yan Zuo, Jing-Liang Li, Wei-Feng Yin, Xue-Ge Pan, Yung-Chi Cheng, Cong-Yuan Xia, Jie-Kun Xu, Wei-Ku Zhang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2026-03-01
Rangatū:	Microbiome
Ngā marau:	Loganin Muribaculum intestinale Gut microbiome Depression Th17 cells Microglia
Urunga tuihono:	https://doi.org/10.1186/s40168-026-02354-4
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!