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CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing

Abstract Background A growing number of studies have focused on investigating circRNAs as crucial regulators in the progression of multiple cancer types. Nevertheless, the biological effects and underlying mechanisms of circRNAs in pancreatic ductal adenocarcinoma (PDAC) remain unclear. Methods Diff...

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Principais autores: Peng Shen, Taoyue Yang, Qun Chen, Hao Yuan, Pengfei Wu, Baobao Cai, Lingdong Meng, Xumin Huang, Jiaye Liu, Yihan Zhang, Weikang Hu, Yi Miao, Zipeng Lu, Kuirong Jiang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-03-01
Serier:Molecular Cancer
Fag:
Pancreatic ductal adenocarcinoma
circNEIL3
miR-432-5p
ADAR1
GLI1
RNA editing
Online adgang:https://doi.org/10.1186/s12943-021-01333-7
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