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CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing

Abstract Background A growing number of studies have focused on investigating circRNAs as crucial regulators in the progression of multiple cancer types. Nevertheless, the biological effects and underlying mechanisms of circRNAs in pancreatic ductal adenocarcinoma (PDAC) remain unclear. Methods Diff...

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Hlavní autoři: Peng Shen, Taoyue Yang, Qun Chen, Hao Yuan, Pengfei Wu, Baobao Cai, Lingdong Meng, Xumin Huang, Jiaye Liu, Yihan Zhang, Weikang Hu, Yi Miao, Zipeng Lu, Kuirong Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2021-03-01
Edice:Molecular Cancer
Témata:
Pancreatic ductal adenocarcinoma
circNEIL3
miR-432-5p
ADAR1
GLI1
RNA editing
On-line přístup:https://doi.org/10.1186/s12943-021-01333-7
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