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Spatial computational modelling illuminates the role of the tumour microenvironment for treating glioblastoma with immunotherapies

Abstract Glioblastoma is the most common and deadliest brain tumour in adults, with a median survival of 15 months under the current standard of care. Immunotherapies like immune checkpoint inhibitors and oncolytic viruses have been extensively studied to improve this endpoint. However, most thus fa...

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Principais autores: Blanche Mongeon, Julien Hébert-Doutreloux, Anudeep Surendran, Elham Karimi, Benoit Fiset, Daniela F. Quail, Logan A. Walsh, Adrianne L. Jenner, Morgan Craig
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-08-01
Series:npj Systems Biology and Applications
Acceso en liña:https://doi.org/10.1038/s41540-024-00419-4
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