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Chimeric oligonucleotides combining guide RNA and single-stranded DNA repair template effectively induce precision gene editing

The ability to precisely alter the genome holds immense potential for molecular biology, medicine and biotechnology. The development of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) into a genomic editing tool has vastly simplified genome engineering. Here, we explored the u...

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Autores principales: Avantika Ghosh, Ksenia Myacheva, Marisa Riester, Carla Schmidt, Sven Diederichs
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis Group 2022-12-01
Colección:RNA Biology
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Acceso en línea:http://dx.doi.org/10.1080/15476286.2022.2067713
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