Hemagglutinin Protease HapA Associated With Vibrio cholerae Outer Membrane Vesicles (OMVs) Disrupts Tight and Adherens Junctions

ABSTRACT This study explores the virulence mechanisms of Vibrio cholerae, with a particular emphasis on HapA, a zinc metalloprotease delivered via outer membrane vesicles (OMVs). The findings reveal that OMV‐associated HapA disrupts the integrity of tight and adherens junctions in intestinal epithel...

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Auteurs principaux:	Palwasha Baryalai, David Irenaeus, Eric Toh, Madeleine Ramstedt, Bernt Eric Uhlin, Aftab Nadeem, Sun Nyunt Wai
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2025-05-01
Collection:	Journal of Extracellular Vesicles
Sujets:	adherens junctions cholera outer membrane vesicles protease tight junctions virulence
Accès en ligne:	https://doi.org/10.1002/jev2.70092
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