Hif1α-dependent mitochondrial acute O2 sensing and signaling to myocyte Ca2+ channels mediate arterial hypoxic vasodilation

Abstract Vasodilation in response to low oxygen (O2) tension (hypoxic vasodilation) is an essential homeostatic response of systemic arteries that facilitates O2 supply to tissues according to demand. However, how blood vessels react to O2 deficiency is not well understood. A common belief is that a...

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Detalhes bibliográficos

Principais autores:	Alejandro Moreno-Domínguez, Olalla Colinas, Ignacio Arias-Mayenco, José M. Cabeza, Juan L. López-Ogayar, Navdeep S. Chandel, Norbert Weissmann, Natascha Sommer, Alberto Pascual, José López-Barneo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-08-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-024-51023-3
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