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Corilagin alleviates atherosclerosis by inhibiting NLRP3 inflammasome activation via the Olfr2 signaling pathway in vitro and in vivo

IntroductionAtherosclerosis, a leading cause of global cardiovascular mortality, is characterized by chronic inflammation. Central to this process is the NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome, which significantly influences atherosclerotic progression. Recent research has...

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Principais autores: Jinqian Mao, Yunfei Chen, Qiushuo Zong, Cuiling Liu, Jiao Xie, Yujie Wang, David Fisher, Nguyen Thi Thu Hien, Khrystyna Pronyuk, Erkin Musabaev, Yiqing Li, Lei Zhao, Yiping Dang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-05-01
Serier:Frontiers in Immunology
Fag:
atherosclerosis
inflammation
Olfr2
NLRP3 inflammasome
corilagin
therapeutic strategies
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1364161/full
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