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A murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletions

<p>Abstract</p> <p>Background</p> <p>To generate a replication-competent retrovirus that could be conditionally inactivated, we flanked the viral genes of the Akv murine leukemia virus with LoxP sites. This provirus can delete its envelope gene by LoxP/Cre mediated recombination and thereby allow su...

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Bibliografische gegevens
Hoofdauteurs: Pedersen Finn, Malek Tiffany, Hodgson J Graeme, Wang Clifford L, Wabl Matthias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2004-04-01
Reeks:Retrovirology
Online toegang:http://www.retrovirology.com/content/1/1/5
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