TFAP4 exacerbates pathological cardiac fibrosis by modulating mechanotransduction

Cardiac fibroblast (CF) differentiation into myofibroblasts is a crucial driver of cardiac fibrosis, leading to extensive extracellular matrix (ECM) deposition that increases myocardial stiffness and eventually impairs heart function. Mechanotransduction has merged as a key regulator of CF activatio...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Jie Liu, Jingjing Feng, Jingxuan Zhao, Xiangjie Kong, Zhangyi Yu, Yuanru Huang, Zechun He, Mengxin Liu, Zheng Liu, Zhibing Lu, Li Wang
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2025-08-01
Sarja:	Cell Insight
Aiheet:	Cardiac fibrosis Fibroblast activation Mechanotransduction TFAP4
Linkit:	http://www.sciencedirect.com/science/article/pii/S2772892725000306
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