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PBMC transcriptomic signatures reflect Trypanosoma cruzi strain diversity and trained immunity in chronically infected macaques

Chagas disease is a tropical disease caused by Trypanosoma cruzi with clinical presentations ranging from asymptomatic to cardiac and/or gastrointestinal complications. The mechanisms of pathogenesis are still poorly understood, but T. cruzi strain diversity may be associated with disease progressio...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Hans Desale, Weihong Tu, Kelly Goff, Preston A. Marx, Claudia Herrera, Eric Dumonteil
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: American Society for Clinical investigation 2025-02-01
Цуврал:JCI Insight
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1172/jci.insight.186003
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