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PBMC transcriptomic signatures reflect Trypanosoma cruzi strain diversity and trained immunity in chronically infected macaques

Chagas disease is a tropical disease caused by Trypanosoma cruzi with clinical presentations ranging from asymptomatic to cardiac and/or gastrointestinal complications. The mechanisms of pathogenesis are still poorly understood, but T. cruzi strain diversity may be associated with disease progressio...

詳細記述

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書誌詳細
主要な著者: Hans Desale, Weihong Tu, Kelly Goff, Preston A. Marx, Claudia Herrera, Eric Dumonteil
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical investigation 2025-02-01
シリーズ:JCI Insight
主題:
オンライン・アクセス:https://doi.org/10.1172/jci.insight.186003
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