Fetal Zika virus inoculation in macaques revealed control of the fetal viral load during pregnancy

Abstract Background Early pregnancy Zika virus (ZIKV) infection is associated with major brain damage in fetuses, leading to microcephaly in 0.6–5.0% of cases, but the underlying mechanisms remain largely unknown. Methods To understand the kinetics of ZIKV infection during fetal development in a non...

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Bibliografische Detailangaben

Hauptverfasser:	Charles Egloff, Claire-Maëlle Fovet, Jessica Denis, Quentin Pascal, Laetitia Bossevot, Sophie Luccantoni, Marco Leonec, Nathalie Dereuddre-Bosquet, Isabelle Leparc-Goffart, Roger Le Grand, Guillaume André Durand, Cyril Badaut, Olivier Picone, Pierre Roques
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-09-01
Schriftenreihe:	Virology Journal
Schlagworte:	TORCH infection Viral clearance Microcephaly Neutralizing antibodies Nonhuman primate model Zika virus
Online-Zugang:	https://doi.org/10.1186/s12985-024-02468-x
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