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Fetal Zika virus inoculation in macaques revealed control of the fetal viral load during pregnancy

Abstract Background Early pregnancy Zika virus (ZIKV) infection is associated with major brain damage in fetuses, leading to microcephaly in 0.6–5.0% of cases, but the underlying mechanisms remain largely unknown. Methods To understand the kinetics of ZIKV infection during fetal development in a non...

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Kaydedildi:
Asıl Yazarlar: Charles Egloff, Claire-Maëlle Fovet, Jessica Denis, Quentin Pascal, Laetitia Bossevot, Sophie Luccantoni, Marco Leonec, Nathalie Dereuddre-Bosquet, Isabelle Leparc-Goffart, Roger Le Grand, Guillaume André Durand, Cyril Badaut, Olivier Picone, Pierre Roques
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2024-09-01
Seri Bilgileri:Virology Journal
Konular:
TORCH infection
Viral clearance
Microcephaly
Neutralizing antibodies
Nonhuman primate model
Zika virus
Online Erişim:https://doi.org/10.1186/s12985-024-02468-x
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