Exposure–Response Analysis of Donidalorsen for the Treatment of Hereditary Angioedema
ABSTRACT Hereditary angioedema (HAE) is characterized by recurrent attacks of severe tissue swelling. In the OASIS‐HAE phase 3 study (NCT05139810), donidalorsen, an RNA‐targeted antisense oligonucleotide that reduces prekallikrein production in the liver, significantly reduced HAE attack rates. To c...
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| Автори: | , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Wiley
2025-11-01
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| Серія: | Clinical and Translational Science |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1111/cts.70388 |
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