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Antigenic extracts of Leishmania braziliensis and Leishmania amazonensis associated with saponin partially protects BALB/c mice against Leishmania chagasi infection by suppressing IL-10 and IL-4 production

This study evaluated two vaccine candidates for their effectiveness in protecting BALB/c mice against Leishmania chagasiinfection. These immunogenic preparations were composed of Leishmania amazonensisor Leishmania braziliensisantigenic extracts in association with saponin adjuvant. Mice were given...

Täydet tiedot

Tallennettuna:
Päätekijät: Rafaella FQ Grenfell, Eduardo A Marques-da-Silva, Miriam C Souza-Testasicca, Eduardo AF Coelho, Ana Paula Fernandes, Luís Carlos C Afonso, Simone A Rezende
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Fundação Oswaldo Cruz (FIOCRUZ) 2010-09-01
Sarja:Memorias do Instituto Oswaldo Cruz
Aiheet:
vaccine
Leishmania chagasi
Leishmania braziliensis
Leishmania amazonensis
IL-10
IL-4
Linkit:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000600015
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