Antigenic extracts of Leishmania braziliensis and Leishmania amazonensis associated with saponin partially protects BALB/c mice against Leishmania chagasi infection by suppressing IL-10 and IL-4 production

This study evaluated two vaccine candidates for their effectiveness in protecting BALB/c mice against Leishmania chagasiinfection. These immunogenic preparations were composed of Leishmania amazonensisor Leishmania braziliensisantigenic extracts in association with saponin adjuvant. Mice were given...

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Autors principals:	Rafaella FQ Grenfell, Eduardo A Marques-da-Silva, Miriam C Souza-Testasicca, Eduardo AF Coelho, Ana Paula Fernandes, Luís Carlos C Afonso, Simone A Rezende
Format:	Artigo
Idioma:	Inglês
Publicat:	Fundação Oswaldo Cruz (FIOCRUZ) 2010-09-01
Col·lecció:	Memorias do Instituto Oswaldo Cruz
Matèries:	vaccine Leishmania chagasi Leishmania braziliensis Leishmania amazonensis IL-10 IL-4
Accés en línia:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000600015
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