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A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?

VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous spaces of the placenta, leading to placental malaria (PM). Relatively high polymorphism in VAR2CSA sequences has hindered...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Justin Y A Doritchamou, Jonathan P Renn, Lars Hviid, Patrick E Duffy
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2023-05-01
Rangatū:PLoS Pathogens
Urunga tuihono:https://doi.org/10.1371/journal.ppat.1011370
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